Clinical effects of Polygonum cuspidatum on patients with type 2 diabetes mellitus of Dampness-Heat Pattern
10.3969/j.issn.1001-1528.2024.08.016
- VernacularTitle:虎杖对湿热证2型糖尿病患者的临床疗效
- Author:
Yuan-Ying XU
1
;
Wen-Wen KONG
;
Hong-Ping YIN
;
Hui-Hui ZHANG
;
Xing-Hua CAI
;
Bi-Lin XU
;
Wen-Jun SHA
;
Tao LEI
Author Information
1. 上海中医药大学附属普陀医院内分泌科,上海 200062
- Keywords:
Polygonum cuspidatum Sieb.et Zucc.;
conventional treatment;
type 2 diabetes mellitus;
Dampness-Heat Pattern
- From:
Chinese Traditional Patent Medicine
2024;46(8):2596-2600
- CountryChina
- Language:Chinese
-
Abstract:
AIM To explore the clinical effects of Polygonum cuspidatum Sieb.et Zucc.on patients with type 2 diabetes mellitus of Dampness-Heat Pattern.METHODS One hundred and forty patients were randomly assigned into control group(70 cases)for 8-week intervention of conventional treatment,and observation group(70 cases)for 8-week intervention of both P.cuspidatum granules and conventional treatment.The changes in body weight,BMI,blood glucose indices(FBG,2 h PG,HbA1C,GA),blood lipid indices(TC,TG,HDL-C,LDL-C,ApoA-I,ApoB,ApoA,ApoE,sdLDL-C),liver function indices(ALT,AST),fatty liver progression,TyG,HSI,TCM syndrome score and effects were detected.RESULTS The observation group demonstrated higher total effective rates of TCM syndromes than the control group(P＜0.01),along with slighter fatty liver progression(P＜0.01).After the treatment,the observation group displayed decreased body weight,BMI,FBG,GA,TG,ApoE,TyG,HSI,ALT and TCM syndrome score(P＜0.05,P＜0.01),and 2 h PG,TyG,HSI,ALT,TCM syndrome score were lower than those in the control group(P＜0.05,P＜0.01).CONCLUSION For the patients with type 2 diabetes mellitus of Dampness-Heat Pattern,P.cuspidatum can improve glucose and lipid metabolism disorders,which is worthy of clinical popularization and application.
