Chemical constituents from the ethyl acetate fraction of Baccharis trimera
10.3969/j.issn.1001-1528.2024.06.022
- VernacularTitle:巴西酒神菊乙酸乙酯部位化学成分研究
- Author:
Yong LIANG
1
;
Xiao-Qing ZHOU
;
Li-Ping TANG
;
Xue-Mei GAO
;
Dong-Mei YAN
;
Xiao-Tian CHEN
;
Dian XU
;
Bin LI
;
Hong-Dong LIU
Author Information
1. 江西中医药大学院士工作站,江西南昌 330004
- Keywords:
Baccharis trimera(Less.)DC;
ethyl acetate fraction;
chemical constituents;
isolation and identification
- From:
Chinese Traditional Patent Medicine
2024;46(6):1906-1913
- CountryChina
- Language:Chinese
-
Abstract:
AIM To study the chemical constituents from the ethyl acetate fraction of Baccharis trimera(Less.)DC.METHODS The ethyl acetate fraction of B.trimera was isolated and purified by macroporous resin D101,Sephadex LH-20 gel,silica gel and other chromatographic techniques,then the structures of obtained compounds were identified by physicochemical properties and spectral data.RESULTS Twenty-three compounds were isolated and identified as 15,16-epoxy-15α-methoxy-ent-clerod-3-en-18-oic acid(1),13-epi-15,16-epoxy-15α-methoxy-ent-clerod-3-en-18-oic acid(2),methyltrineracetal(3),epimethyltrineracetal(4),trinerolide(5),15-epitrinerolide(6),18-methylmalonyl-7α-hydroxy-meth-yltrineracetal(7),18-methylmalonyl-7α-hydroxy-epimethyltriner-acetal(8),18-methylmalonyl-methyltrineracetal(9),18-methylmalonyl-epi-methyltrineracetal(10),methy 3,5-dicaffeoylquinate(11),8-dimetho-xyflavone(12),4',7-dihydroxy-5-methoxyflavanone(13),4-(3',4'-dihydroxycinna-moyl)-oxy-methy-lcinnamate(14),3',7-dihydroxy-4',6,8-trimethoxy-flavone(15),erigeroflavanone(16),nepetin(17),4,2',4',β-tetrahydroxy-6'-methoxy-α,β-dihydrochalcone(18),eugeniyl-O-β-D-glucoside(19),7-hydroxyl-5,6,3',4'-tetramethoxylflavone(20),phomoxanthone J(21),18-acetyl-7α-hydroxy-methyltrineracetal(22),18-acetyl-7α-hydroxy-epimethyltrineracetal(23).CONCLUSION Compounds 3-10 and 22-23 are epimers isolated from this plant for the first time.Compounds 11-16,18-21 are first isolated from genus Baccharis.
