Flavonoids from the leaves of Cinnamomum camphora and their antioxidant activities
10.3969/j.issn.1001-1528.2024.06.019
- VernacularTitle:樟叶黄酮类成分及其抗氧化活性研究
- Author:
Peng-Fei YANG
1
;
Jin-Hong WEI
;
Yü-Mei QIAN
;
Zheng-Guang SUN
;
Wei WU
;
Shen HUANG
;
Jia-Xiang FEI
;
Duo-Bin MAO
Author Information
1. 郑州轻工业大学烟草科学与工程学院,河南郑州 451000
- Keywords:
Cinnamomum camphora(L.)Presl;
leaves;
flavonoids;
isolation and purification;
antioxidant activities
- From:
Chinese Traditional Patent Medicine
2024;46(6):1889-1894
- CountryChina
- Language:Chinese
-
Abstract:
AIM To study the flavonoids from the leaves of Cinnamomum camphora(L.)Presl.and their antioxidant activities.METHODS The 95％ethanol extraction from the leaves of C.camphora was isolated and purified by liquid-liquid extraction,macroporous adsorption resin chromatography,HW-40C gel column chromatography,molecular exclusion chromatography and preparative HPLC,then the structures of obtained compounds were identified by physicochemical properties and spectral data.The antioxidant activity was determined by DPPH method.RESULT Ten flavonoids were isolated and identified as(2R,3S)-7-methoxy-5-O-β-D-glucopyranosyl-afzelechin(1),quercetin-3-O-sambubioside(2),quercetin-3-O-β-D-apiosyl-(1→2)-β-D-glucoside(3),quercetin-3-O-robibioside(4),kaempferol-3-O-β-D-rutinoside-7-O-β-D-glucoside(5),kaempferol-3-O-α-L-rhamnoside-7-O-β-D-glucoside(6),5,3'-di-O-methyl-epicatechin(7)、cinchonain Ⅱb(8)、quercetin-3,4'-di-O-β-D-glucoside(9)、(-)-epicatechin(10).The IC50 value of compound 8 scavenging DPPH free radical was 4.8 μg/mL.CONCLUSION Compound 1 is a new compound,and compound 2-6 are obtained from Cinnamomum genus for the first time,compound 7-9 are first isolated from this plant.Compound 8 shows good antioxidant activities..
