Effect and safety of electroacupuncture in the treatment of chronic prostatitis/chronic pelvic pain syndrome:A systematic review and meta-analysis of 17 randomized controlled trials
10.13263/j.cnki.nja.2024.10.010
- VernacularTitle:电针治疗慢性前列腺炎/慢性盆腔疼痛综合征的有效性和安全性:17项随机对照试验的系统评价和meta分析
- Author:
Jun-Tao LI
1
;
Lu-Yu LI
;
Xiao LI
;
Feng LIU
;
Miao-Miao MA
;
Bao-Jun JU
Author Information
1. 河南中医药大学第一附属医院男科,河南郑州 450000
- Keywords:
electroacupuncture;
chronic prostatitis/chronic pelvic pain syndrome;
meta-analysis;
randomized controlled trial;
systematic review
- From:
National Journal of Andrology
2024;30(10):921-930
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To systematically evaluate the effect and safety of electroacupuncture in the treatment of chronic prostati-tis/chronic pelvic pain syndrome(CP/CPPS).Methods:We searched the major Chinese and English databases of CNKI,Wan-fang Data,VIP,CBM,PubMed,Cochrane Library,Web of Science and Embase for randomized controlled trials(RCT)on electroa-cupuncture or combination therapy in the treatment of CP/CPPS published from the establishment of the databases to August 2024.The dichotomous data and continuous data were represented by risk ratio(RR)and mean difference(MD)respectively,both with 95％confidence interval(CI).We analyzed the data with the Revman(v.5.4)software and assessed the quality of the evidence in each RCT using the Grading of Recommendations Assessment,Development and Evaluation system(GRADE).Results:Totally 17 RCTs were identified,involving 1 404 cases of CP/CPPS treated by electroacupuncture or combination of electroacupuncture with medication or with other therapies(the trial group)or by medication with Western or Chinese drugs alone(the control group).Compared with the control group,the trial group showed a significantly higher rate of clinical effectiveness(RR=1.25;95％CI:1.18-1.32;P＜0.05),decreased CPSI scores(MD=-4.56;95％CI:-5.01--4.11;P＜0.05),improved CPSI-pain,-urination and-quali-ty of life scores,and increased maximum and average urinary flow rates.And electroacupuncture did not increase the likelihood of ad-verse reactions.Conclusion:Medium-quality evidence suggests that electroacupuncture is beneficial complementary and alternative therapy for CP/CPPS,with a significant advantage in improving the NIH-CPSI scores of the patients.However,more high-quality multi-centered RCTs with larger sample sizes are still needed to further verify the effect of electroacupuncture on CP/CPPS.
