Ferroptosis in the testis:Progress in research
10.13263/j.cnki.nja.2024.07.014
- VernacularTitle:铁死亡在睾丸中的研究进展
- Author:
Wen-Xiu ZHANG
1
;
Da-Lin SUN
;
Bao-Fang JIN
Author Information
1. 青海大学,青海 西宁 810016
- Keywords:
ferroptosis;
testis;
cell death;
oxidative stress;
high-risk factors
- From:
National Journal of Andrology
2024;30(7):663-667
- CountryChina
- Language:Chinese
-
Abstract:
Ferroptosis is a form of cell death resulting from the disruption of iron metabolism within cells and excessive accumu-lation of lipid peroxides.Research indicates that,under the influence of various pathogenic factors,ferroptosis impacts the male repro-ductive system and fertility by affecting the synthesis of testicular hormones and regulation of cellular functions through different path-ways and numerators.This paper provides an overview of the action mechanisms of ferroptosis in the testis and its correlation with path-ogenicity,offering some new insights into the treatment of male reproductive system diseases.
