Dongbai Tonglin Mixture for the treatment of chronic prostatitis
10.13263/j.cnki.nja.2024.04.008
- VernacularTitle:冬柏通淋合剂治疗慢性前列腺炎的临床观察
- Author:
Juan LIU
1
;
Wei XIA
;
Ze-Huan YUAN
;
Wen-Jun HAN
Author Information
1. 上海中医药大学附属第七人民医院药学部,上海 200137
- Keywords:
Dongbai Tonglin Mixture;
chronic prostatitis;
damp-heat downward diffusion syndrome;
clinical observation
- From:
National Journal of Andrology
2024;30(4):336-341
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the efficacy of Dongbai Tonglin Mixture(DTM)in the treatment of chronic prostatitis(CP)with the damp-heat downward diffusion syndrome.Methods:We randomly selected 76 cases of CP with the damp-heat downward dif-fusion syndrome,equally divided them into a DTM and a control group,and treated them by oral administration of DTM and Qianlie Tai Tablets,respectively,both for 8 weeks.We obtained the NIH-CPSI and TCM Syndrome Scores of the patients,recorded the counts of white blood cells(WBC)and small particles of lecithin(SPL)in the prostate fluid,and compared them between the two groups before and after treatment.Results:Compared with the baseline,the total NIH-CPSI scores were significantly reduced in both groups after treatment(P<0.05),particularly the scores on urination symptoms,pain/discomfort and quality of life(P<0.05),even more sig-nificantly in the DTM than in the control group(P<0.05),and so were the TCM Syndrome Scores(P<0.05),especially the scores on urinary incontinence,abdominal pain,perineal pain,and scrotal dampness(P<0.05),even more significantly in the former than in the latter group(P<0.05).The count of WBC in the prostate fluid was remarkably decreased(P<0.05),while that of SPL markedly increased in both groups after treatment(P<0.05),with an even more significant improvement in the DTM than in the con-trol group(P<0.05),and the overall effectiveness rate of treatment was significantly higher in the former group than in the latter(88.89%vs 70.27%,P<0.05).Conclusion:Dongbai Tonglin Mixture is effective for the treatment of CP with the damp-heat downward diffusion syndrome.
