Research progress on the correlation between gut microbiota and male infertility
10.13263/j.cnki.nja.2023.05.012
- VernacularTitle:肠道菌群失调与男性不育相关性的研究进展
- Author:
Xu SUN
1
;
Ping CHENG
;
Guang-Hui ZANG
Author Information
1. 蚌埠医科大学研究生院,安徽蚌埠 233000
- Keywords:
gut microbiota;
male infertility;
immune system;
insulin resistance;
semen quality
- From:
National Journal of Andrology
2023;29(5):450-454
- CountryChina
- Language:Chinese
-
Abstract:
Male infertility is one of the serious problems currently affecting human reproduction and health.Healthy gut microbi-ota is involved in the development of the immune system and protection against pathogen invasion,and it maintain normal metabolism and improve reproductive potential by secreting a variety of substances.The imbalance of gut microbiota can promote the local and sys-temic immune inflammatory response,induce chronic metabolic diseases,affect the synthesis of sex hormones,cause abnormal sper-matogenesis,maturation or activation,and it is closely related to the decline of male fertility.By exploring the correlation between gut microbiota and male infertility,this paper aims to provide new clues and directions for the clinical diagnosis and treatment of male in-fertility.
