Clinical Analysis on the Treatment of Prostate Cancer
10.3969/j.issn.1009-3591.2001.02.005
- VernacularTitle:中晚期前列腺癌临床治疗分析
- Author:
YAO XIN
1
;
DONG LIXIN
;
LI WENLU
;
ZHANG LI
;
JIA WEIYING
;
MA TENGXIANG
Author Information
1. Tianjin Medical University
- From:
National Journal of Andrology
2001;7(2):90-93
- CountryChina
- Language:Chinese
-
Abstract:
Objectives: To investigate the effect of radiation therapy,hormonal therapy,and to combinations of these modalities on local advanced and metastatic prostatecancer,and to evaluate the diagnostic value of PSA. Methods: Fifty patients withprostate cancer up stage C (from 1986 to 1997) were studied retrospectively.According to the different treatment, these cases were divided into 4 groups,and thesurvival rates among these groups and the variation of serum PSA levels between pre-and post-therapeutics were compared. Results: The PSA of >93.7% patients was >4μg/Land the serum level decreased 80%～86% after endocrinology therapy(P<0.05).The 2-and 5- year survival rates for stage C patients after surgical ablation were 100%and 66%, while those for stage D were 81% and 36%. In the group of radiation, thesurvival rates were 100%,50% for stage C and 50%,0 for stage D. In the group ofcombined treatment,2-year survival rate is 100%,and 5-year was 77%. Conclusions: PSAis a sensitive marker for diagnosis and prognosis of prostate cancer.Radiationcombined hormonal therapy is more effective than any single treatment. For stage D,hormonal therapy is better than radiation. Natl J Androl,2001,7(2):90～93
