Percutaneous transhepatic papillary balloon dilation combined with dual-frequency double-pulse laser lithotripsy for large-diameter common bile duct stones
10.3760/cma.j.cn112138-20231201-00358
- VernacularTitle:经皮经肝十二指肠乳头肌扩张顺行排石术联合双频双脉冲激光碎石治疗大直径胆总管结石
- Author:
Yiran SUN
1
;
Tao JIANG
;
Honggang SHANG
;
Gang CHEN
;
Wei WANG
;
Yongzheng WANG
;
Yuliang LI
;
Wujie WANG
Author Information
1. 山东大学第二医院介入与肿瘤微创治疗科 山东大学齐鲁医学院，济南 250033
- Keywords:
Choledocholithiasis;
Radiology, interventional;
Ureteroscopes;
Lasers
- From:
Chinese Journal of Internal Medicine
2024;63(10):982-986
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the safety and efficacy of percutaneous transhepatic papillary balloon dilation (PTPBD) combined with flexible ureteroscopy-guided dual-frequency double-pulse ND:YAG (FREDDY) laser lithotripsy (PTPBD-FREDDY) for the treatment of giant (>1.5 cm diameter) common bile duct stones.Methods:A retrospective analysis was conducted on 26 patients with large-diameter difficult choledocholithiasis admitted to two medical centers from December 2017 to October 2021. Among these patients, four could not tolerate surgery or endoscopic treatment, six experienced failure of endoscopic treatment, and 16 refused to undergo endoscopic or surgical treatment. All patients underwent the PTPBD-FREDDY procedure. The FREDDY laser lithotripsy was performed under ureteroscopic guidance, followed by a balloon to push the stones into the duodenum. The primary endpoint was the technical success rate, and the secondary endpoints included the rate of stone recurrence and related complications.Results:All 26 patients successfully completed the operation, achieving a technical success rate of 100%. The average lithotripsy frequency and operation time for bilirubin stones were significantly higher than those of mixed stones and cholesterol stones ( P<0.01). The main postoperative complications included mild fever ( n=3), abdominal pain ( n=3), nausea ( n=2) and vomiting ( n=1). One patient experienced biliary tract bleeding, which improved after conservative treatment. No serious complications such as pancreatitis, sepsis, or biliary perforation were observed. After 2 years of follow-up, no cases of stone recurrence were observed. Conclusions:PTPBD-FREDDY is a safe and effective treatment for patients with giant common bile duct stones. It provides a new therapeutic option for patients with giant choledocholithiasis who can not tolerate surgery or have failed endoscopic treatment, demonstrating promising prospects.
