Correlation of TyG index combined with monocyte-to-high-density lipoprotein cholesterol ratio and severity of coronary artery lesions in patients with type 2 diabetes mellitus
10.3760/cma.j.cn311282-20230904-00061
- VernacularTitle:TyG指数联合单核细胞与高密度脂蛋白胆固醇比值与2型糖尿病患者冠状动脉病变严重程度的相关性研究
- Author:
Jianping FU
1
;
Xue WANG
;
Yuanyuan NIU
;
Lina MOU
;
Yong LI
;
Jing LI
;
Huijing ZHANG
Author Information
1. 衡水市人民医院心血管内科 053000
- Keywords:
Diabetes mellitus, type 2;
Coronary arteries;
Triglyceride-glucose index;
Monocytes/high-density lipoprotein cholesterol ratio
- From:
Chinese Journal of Endocrinology and Metabolism
2024;40(10):867-871
- CountryChina
- Language:Chinese
-
Abstract:
Patients with type 2 diabetes mellitus (T2DM) typically have a higher risk of cardiovascular diseases, including coronary artery disease (CAD). Currently, the gold standard for diagnosing the severity of coronary artery lesions in T2DM patients is coronary angiography (CAG). This retrospective analysis reviewed data from T2DM patients who underwent CAG at Hengshui People′s Hospital between May 2020 and July 2022. Utilizing multivariate logistic regression analysis, factors associated with the severity of coronary artery stenosis in T2DM patients were identified. Based on these findings, a predictive model was developed to evaluate CAD severity in T2DM patients, incorporating smoking history, elevated triglyceride-glucose (TyG) index, and elevated monocyte to high-density lipoprotein cholesterol ratio (MHR). The combination of the TyG index and MHR model provides insights into coronary artery stenosis severity in T2DM patients, potentially reducing unnecessary invasive CAG procedures.
