Renal diabetes insipidus caused by Sj?gren′s syndrome
10.3760/cma.j.cn311282-20230919-00084
- VernacularTitle:干燥综合征引起的肾性尿崩症
- Author:
Xiaoxia LIU
1
;
Lijin JI
;
Lingbiao WANG
;
Lin LU
;
Yu XUE
;
Jun XUE
;
Yiming LI
;
Bin LU
Author Information
1. 复旦大学附属华山医院内分泌科，上海 200040
- Keywords:
Nephrogenic diabetes insipidus;
Primary Sj?gren′s syndrome;
Renal tubular acidosis;
Hypokalemia
- From:
Chinese Journal of Endocrinology and Metabolism
2024;40(8):697-701
- CountryChina
- Language:Chinese
-
Abstract:
We present a case of nephrogenic diabetes insipidus secondary to primary Sj?gren′s syndrome. At onset, the patient exhibited a urine output of up to 10 liter per day. Diagnostic evaluation and clinical features confirmed renal diabetes insipidus due to primary Sj?gren′s syndrome. A review of the literature indicates that primary Sj?gren′s syndrome can involve renal manifestations, including renal tubulointerstitial inflammation and impaired renal concentration ability. However, nephrogenic diabetes insipidus with such high urine output is uncommon. Management of this condition requires proactive control of the underlying disease, potassium supplementation, and urine management.
