Relationship between dietary patterns and metabolism-associated fatty liver disease subtype in adult
10.3760/cma.j.cn311282-20240130-00048
- VernacularTitle:成年人膳食模式与代谢相关脂肪性肝病亚型的关联性
- Author:
Manling HU
1
;
Xinlei MIAO
;
Qianqian WANG
;
Xiaoling XIE
;
Ziping SONG
;
Shuang LIU
;
Song LENG
Author Information
1. 大连医科大学附属第二医院健康管理中心，大连 116023
- Keywords:
Metabolic fatty liver disease;
Dietary pattern;
Health examination;
Factor analysis;
Multiplicative interaction
- From:
Chinese Journal of Endocrinology and Metabolism
2024;40(5):398-406
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the association between different dietary patterns and subtypes of metabolic associated fatty liver disease(MAFLD).Methods:A total of 6 022 check-ups at the health management center of the Second Hospital of Dalian Medical University from January 2022 to March 2023 were selected as study subjects. MAFLD was categorised into three subtypes: overweight/obese type, metabolic disorder type, and diabetic type. Factor analysis was used to extract dietary patterns. Logistic regression was used to assess the impact of dietary patterns on MAFLD occurrence, constructing interaction models between dietary patterns intake and age, gender, and physical exercise levels. Results:Four dietary patterns were extracted based on feature sorting after factor analysis and were named as the high-quality protein pattern, the fruit-vegetable pattern, egg-aquatic pattern, and the processed meat pattern. Regression analysis of the unadjusted model showed that overweight/obese and diabetic types of MAFLD were negatively associated with the high-quality protein mode, while model-adjusted regression analysis showed that the processed meat pattern was positively associated with the risk of MAFLD, and fruit-vegetable pattern was positively associated with overweight/obese MAFLD( P<0.05). The results of subgroup analyses suggested that female( OR=1.55, 95% CI 1.14-2.15) with a high intake of pickle pattern had a higher risk of overweight/obese MAFLD than male( OR=1.18, 95% CI 1.02-1.49). Conclusion:High-quality protein pattern was negatively correlated with MAFLD, whereas fruit-vegetable pattern and processed meat pattern were positively correlated with MAFLD. Female with high consumption of processed meat pattern are more likely to develop overweight/obesity MAFLD compared with male. It is recommended that people with MAFLD reduce their intake of processed products and high-fructose food, and consume adequate amounts of high-quality protein food to maintain a balanced diet.
