Effect of electroacupuncture preconditioning on emergence agitation in patients undergoing total laparoscopic hysterectomy
10.3760/cma.j.cn131073.20240611.01106
- VernacularTitle:电针预处理对腹腔镜全子宫切除术患者苏醒期躁动的影响
- Author:
Mintao ZHOU
1
;
Caiju ZHANG
;
Jinhou FU
;
Jinqian HE
;
Qianying QI
;
Ning SUN
;
Bitan ZHANG
Author Information
1. 南阳市第一人民医院 河南大学附属医院麻醉与围术期医学科，南阳 473010
- Keywords:
Electroacupuncture;
Laparoscopes;
Hysterectomy;
Resortification period restlessness
- From:
Chinese Journal of Anesthesiology
2024;44(11):1307-1310
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effect of electroacupuncture preconditioning on emergence agitation in the patients undergoing total laparoscopic hysterectomy.Methods:This was a randomized controlled trial. Ninety American Society of Anesthesiologists Physical Status classification Ⅱ or Ⅲ patients, aged 40-60 yr, with a body mass index of 50-70 kg, scheduled for elective total laparoscopic hysterectomy, were divided into control group (C group) and electroacupuncture preconditioning group (E group) using a random number table method, with 45 patients in each group. At 30 min before anesthesia induction, Zusanli and Neiguan acupoints were stimulated for 30 min with disperse-dense waves at a frequency of 2 Hz/100 Hz, an intensity of 3 mA, in group E. Group C did not receive electroacupuncture treatment. The occurrence of emergence agitation, usage of vasoactive drugs and rescue analgesia were recorded in two groups. Peripheral venous blood samples from the upper extremity were obtained before electroacupuncture stimulation (T 0) and at 2 h after operation (T 1) for determination of the plasma concentrations of C-reactive protein (CRP), tumor necrosis factor-alpha (TNF-α) and interleukin-10 (IL-10) by enzyme-linked immunosorbent assay. Results:The plasma CRP and TNF-α concentrations in group C and plasma IL-10 concentrations in group E were significantly higher at T 1 than at T 0 ( P<0.05). Compared with group C, the usage rate of vasoactive drugs, rate of rescue analgesia, and incidence of emergence agitation were significantly decreased, and the plasma concentrations of CRP and TNF-α were decreased and the plasma IL-10 concentrations were increased at T 1 in group E ( P<0.05). Conclusions:Electroacupuncture preconditioning can decrease the occurrence of emergence agitation in the patients undergoing total laparoscopic hysterectomy, which may be related to inhibiting inflammatory responses.
