Effect of bupivacaine liposome for erector spinae plane block on quality of postoperative recovery in patients undergoing thoracoscopic lung resection
10.3760/cma.j.cn131073.20240523.01003
- VernacularTitle:布比卡因脂质体竖脊肌平面阻滞对胸腔镜肺切除术患者术后恢复质量的影响
- Author:
Xisheng SHAN
1
;
Yang ZHANG
;
Dawei LIAO
;
Jinghui HU
;
Ke PENG
;
Huayue LIU
;
Fuhai JI
Author Information
1. 苏州大学附属第一医院麻醉手术科 苏州大学麻醉学研究所，苏州 215006
- Keywords:
Bupivacaine;
Liposomes;
Nerve block;
Thoracoscopes;
Pneumonectomy;
Rehabilitation;
Erector spinae
- From:
Chinese Journal of Anesthesiology
2024;44(10):1165-1169
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of bupivacaine liposome for erector spinae plane block on the quality of postoperative recovery in patients undergoing thoracoscopic lung resection.Methods:From July 2023 to January 2024, 128 American Society of Anesthesiologists Physical Status classification ⅠorⅡ patients of either sex, aged 18-75 yr, with body mass index of 18-32 kg/m 2, scheduled for elective thoracoscopic lung resection at the First Affiliated Hospital of Soochow University, were assigned to either bupivacaine liposome group (BL group) or bupivacaine hydrochloride group (BH group) using a random number table method, with 64 patients in each group. Patients received an ultrasound-guided erector spinae plane block following anesthesia induction. BL group received an injection of bupivacaine liposome 20 ml (266 mg) plus normal saline 10 ml, while BH group received an injection of bupivacaine hydrochloride 20 ml (100 mg) plus normal saline 10 ml. The primary outcome was the Quality of Recovery-15 (QoR-15) score at 24 h postoperatively. Secondary outcomes included the QoR-15 score at 3 days postoperatively, time to first patient-controlled analgesia press, and total opioid consumption within the first 3 days postoperatively. Other outcomes assessed were the time to ambulation, duration of chest tube placement, length of hospital stay, patient satisfaction scores at discharge, and development of adverse reactions during hospitalization. Results:Compared to BH group, QoR-15 scores were significantly increased at 24 h and 3 days postoperatively, the time to first patient-controlled analgesia press was significantly prolonged, the consumption of opioid was reduced within the first 3 days postoperatively, the time to ambulation was shortened, and patient satisfaction scores at discharge were increased in BL group ( P<0.05). There were no statistically significant differences between the two groups in terms of the chest tube duration, length of hospital stay, and incidence of adverse reactions during hospitalization ( P>0.05). Conclusions:Bupivacaine liposome for erector spinae plane block can improve the quality of postoperative recovery in patients undergoing thoracoscopic lung resection.
