Prepubertal-type testicular neuroendocrine tumor: a case report

VernacularTitle:青春期前型睾丸神经内分泌瘤1例报告
Author: Xinwen ZHANG ¹ ; Xiaoli ZHOU ; Wenxian GU ; Ting LI ; Yuqing CHENG
Author Information

1. 江苏大学附属金坛医院　常州市金坛第一人民医院病理科，常州　213200
Keywords: Testicular neoplasm; Prepubertal-type testicular neuroendocrine tumor; Pathology
From: Chinese Journal of Urology 2024;45(8):635-636
CountryChina
Language:Chinese
Abstract: Prepubertal-type testicular neuroendocrine tumor is a rare neoplasm of low malignant potential, which is classified as germ cell tumors unrelated to germ cell neoplasia in situ, and needs to be differentiated from metastatic neuroendocrine tumor, postpubertal-type testicular neuroendocrine tumor, and testicular seminoma. The clinicopathological and molecular features of a case of prepubertal-type testicular neuroendocrine tumor were reported. The tumour cells were uniform in size and arranged in nested and insular pattern. The tumor was positive for CgA and Syn, and the Ki-67 index was less than 2% by immunostaining. Next-generation sequencing identified no variants of pathogenicity, potential pathogenicity or uncertain significance. The patient was followed without evidence of recurrence and metastasis 56 months after surgery.