Research progress on focal therapy for early-stage renal cell carcinoma
10.3760/cma.j.cn112330-20240322-00145
- VernacularTitle:早期肾癌局灶治疗的研究进展
- Author:
Wenqiang LIU
1
;
Jiaao SONG
;
Tong CHEN
;
Zhenjie WU
;
Linhui WANG
Author Information
1. 海军军医大学第一附属医院，上海 200433
- Keywords:
Kidney neoplasms;
Early;
Focal therapy;
Ablative treatmen
- From:
Chinese Journal of Urology
2024;45(5):397-400
- CountryChina
- Language:Chinese
-
Abstract:
Focal therapy for renal cell carcinoma is a precision treatment technique that directly targets and destroys cancerous lesions while preserving the maximum amount of surrounding healthy kidney tissue through localized intervention. It is primarily indicated for early-stage renal cell carcinoma in patients with tumors ≤4 cm in diameter (T 1a), particularly for those at higher surgical risk. Compared to traditional radical nephrectomy and partial nephrectomy, focal therapy offers several advantages, including lower physical demands on the patient, minimally invasive nature, reduced risk of complications, and faster recovery. The focal therapy techniques currently utilized in clinical practice include cryoablation, radiofrequency ablation, microwave ablation, irreversible electroporation, high-intensity focused ultrasound, and stereotactic body radiotherapy. This article reviews the principles of various focal therapy techniques, patient selection, and the oncological outcomes, complications, and renal function preservation associated with these focal therapies.
