Progress in molecular regulatory mechanisms of adrenal cortical carcinoma
10.3760/cma.j.cn112330-20230325-00092
- VernacularTitle:肾上腺皮质癌分子调控机制研究进展
- Author:
Kaixuan ZHANG
1
;
Jiwen SHANG
;
Yu GONG
Author Information
1. 山西医科大学第三医院 山西白求恩医院 山西医学科学院 同济山西医院泌尿外科，太原 030032
- Keywords:
Adrenocortical carcinoma;
Pathogenesis;
β-catenin;
P53;
Epithelial-mesenchymal transition;
Insulin growth factor(IGF);
Fibroblast growth factor
- From:
Chinese Journal of Urology
2024;45(3):231-234
- CountryChina
- Language:Chinese
-
Abstract:
Adrenocortical carcinoma (ACC) is a rare and highly aggressive endocrine malignancy. This paper provides a review of the pathways involved in the development of ACC and the progress of targeted drug therapy. The pathways reviewed include Wnt/β-catenin, P53, epithelial-mesenchymal transition(EMT), insulin growth factor(IGF) and fibroblast growth factor(FGF) signalling pathways.
