Clear cell renal cell carcinoma with syncytial giant cells: a case report

VernacularTitle:伴合胞体样巨细胞的透明细胞性肾细胞癌1例报告
Author: Wenjia SUN ¹ ; Junqiu YUE ; Lifang FAN
Author Information

1. 华中科技大学同济医学院附属湖北肿瘤医院病理科，武汉　430070
Keywords: Carcinoma, renal cell; Clear cell; Syncytial giant cells; Prognosis
From: Chinese Journal of Urology 2024;45(3):219-220
CountryChina
Language:Chinese
Abstract: Syncytial giant cells (SGCs) are epithelial giant cells with multiple uniform and similar nuclei. Clear cell renal cell carcinoma (ccRCC) with SGCs is a rare microscopic morphology. A 70-year-old man was admitted to hospital with multiple nodules in both lungs found by chest CT examination 2 weeks before. A left renal carcinoma with lung metastasis was considered by PET-CT. Cytoreductive nephrectomy was performed, and postoperative pathological diagnosis confirmed ccRCC with SGCs of the left renal. Combined immunotherapy and targeted therapies were administered. There was no disease progression during follow-up period of 28 months.