The role of muscle-brain axis in the relationship between sarcopenia and cognitive impairment in the elderly
10.3760/cma.j.issn.0254-9026.2024.11.022
- VernacularTitle:肌-脑轴在老年人肌少症与认知功能障碍关系中的作用
- Author:
Qi HUANG
1
;
Jinmei TANG
;
Ling LING
;
Ao ZHU
;
Daohong LI
;
Rong LYU
Author Information
1. 苏州大学附属苏州九院老年医学科，苏州 215200
- Keywords:
Cognition disorders;
Muscle;
Skeletal;
Sarcopenia
- From:
Chinese Journal of Geriatrics
2024;43(11):1502-1506
- CountryChina
- Language:Chinese
-
Abstract:
Frailty is a geriatric syndrome associated with aging, which is characterized by a decrease in the ability to stress and maintain homeostasis after the loss of physiological reserve function, resulting in an increased risk of falls, disability, and even death.Cognitive impairment is a disorder of cognitive function due to a variety of causes, between normal aging and dementia.In the early stages, frailty is a certain reversibility.As the core of physical frailty, sarcopenia has been a research hotspot in recent years.With the deep research on sarcopenia, researchers have found that is closely related to cognitive disorder.Muscle-brain axis may play a role in sarcopenia and cognitive impairment.This article illustrates its possible mechanisms at the crossroad of sarcopenia and cognitive disorder, and to provide reference for exploring new targets for intervention of sarcopenia and cognitive impairment.
