A Case of Pancreatic Acinar Cell Carcinoma.
10.12701/yujm.2008.25.2.128
- Author:
Hwa Jung LEE
1
;
Jun Ho JI
;
Seung Chan PARK
;
Jung Chul PARK
;
Eun Jung CHOI
;
Hye Jin SEO
;
Won Sik LEE
;
Jung Lim LEE
;
Byung Jo BAE
;
Kyung Rak SHON
;
Kyung Hee LEE
Author Information
1. Department of Internal Medicine, Daegu Fatima Hospital, Daegu, Korea.
- Publication Type:Case Report
- Keywords:
Pancreas;
Carcinoma;
Acinar Cell;
Capecitabine
- MeSH:
Abdominal Pain;
Acinar Cells;
Adult;
Carcinoma, Acinar Cell;
Deoxycytidine;
Electrons;
Fluorouracil;
Gastrectomy;
Hepatectomy;
Humans;
Neoplasm Metastasis;
Pancreas;
Pancreatectomy;
Pancreatic Neoplasms;
Recurrence;
Splenectomy;
Capecitabine
- From:Yeungnam University Journal of Medicine
2008;25(2):128-133
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Acinar cell carcinoma is a rare tumor that represents 1~2% of all pancreatic cancers. Clinical and radiologic findings are inconclusive in this disease. Acinar cell carcinoma is characterized by rapid progression and early metastasis, which lead to its poor prognosis. A 41-year-old man was admitted to our hospital for abdominal pain. Abdominal computed tomography (CT) and positron emission tomography-computed tomography (PET-CT) showed a splenic mass, which was being invaded by a pancreatic tail mass and which had increased 18F-fluorodeoxyglucose (FDG) uptake. Primary radical distal pancreatectomy and splenectomy were performed. Pathologic findings revealed an acinar cell carcinoma of the pancreas. The patient underwent a total gastrectomy three months later because of gastric recurrence. Four months later, multiple hepatic metastases were discovered, and the patient underwent a left hepatectomy. During treatment with capecitabine, there was no evidence of tumor progression for 14 months. We report a case of metastatic pancreatic acinar cell carcinoma, which did not progress for an extended period while the patient was being treated with capecitabine.
