Comparative study on ultrasonic images of elderly-onset versus young-onset rheumatoid arthritis
10.3760/cma.j.issn.0254-9026.2024.10.011
- VernacularTitle:老年和青年类风湿关节炎患者超声影像对比研究
- Author:
Cuiping WANG
1
;
Youjing SUN
;
Xiaojing FAN
;
Junhong REN
Author Information
1. 北京医院超声科 国家老年医学中心 中国医学科学院老年医学研究院，北京 100730
- Keywords:
Arthritis;
Rheumatoid;
Ultrasonography;
Osteoarthritis
- From:
Chinese Journal of Geriatrics
2024;43(10):1306-1309
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the clinical and ultrasonic features of elderly-onset rheumatoid arthritis(EORA)and young-onset rheumatoid arthritis(YORA).Methods:A total of 104 patients diagnosed with rheumatoid arthritis were categorized into two groups based on their age of onset: the EORA group, consisting of 70 patients, and the YORA group, consisting of 34 patients.A comparative analysis was conducted on the clinical manifestations, laboratory findings, and ultrasonic images of patients in these two groups.Results:The male ratio in the EORA group was significantly higher than that in the YORA group(24.3% vs.8.8%, P=0.048).There were no statistical differences in the course of disease, DAS28, ESR, CRP, RF, and anti-CCP antibody positive rates between the two groups( P>0.05)when compared with the YORA group.The incidence of osteoarthritis and osteoporosis in the EORA group was significantly higher than that in the YORA group( P=0.018, P=0.011).Ultrasonic results revealed a significantly higher incidence of phalangeal bone erosion in the EORA group compared to the YORA group(14.9% vs.4.3%, P<0.01).Binary logistic regression analysis indicated that different age groups, disease duration, osteoarthritis, and osteoporosis did not have an effect on the ultrasonic changes of synovial hyperplasia, tendonitis, tenosynovitis, and bone erosion in RA patients. Conclusions:There is no significant difference in the clinical disease activity and disease progression between EORA group and YORA group.Additionally, the pattern of joint inflammation involvement is similar in both groups.Ultrasound examinations revealed a higher incidence of bone erosion in finger joints of EORA patients compared to YORA patients.
