Research progress of sodium-glucose cotransporter 2 inhibitor in anti-aging mechanism
10.3760/cma.j.issn.0254-9026.2024.09.019
- VernacularTitle:钠-葡萄糖协同转运蛋白2抑制剂在抗衰老机制中的研究进展
- Author:
Fengxia HAN
1
;
Hao WANG
;
Xiaoxuan NING
Author Information
1. 空军军医大学第一附属医院老年病科，西安 710032
- Keywords:
Sodium-glucose cotransporter 2 inhibitors;
Anti-aging;
Mechanism
- From:
Chinese Journal of Geriatrics
2024;43(9):1210-1215
- CountryChina
- Language:Chinese
-
Abstract:
Sodium-glucose cotransporter 2 inhibitors(SGLT2i)offer numerous benefits for patients with type 2 diabetes.These benefits include lowering blood pressure and glucose levels, regulating blood lipids, improving arteriosclerosis and endothelial function, reducing urinary protein and decreasing uric acid levels.Additionally, SGLT2i has shown positive outcomes in reducing the risk of kidney failure and cardiovascular adverse events in non-diabetic patients.Recent studies have also discovered that SGLT2i has anti-aging effects, which can potentially delay aging and improve age-related diseases.This article provides a comprehensive review of the potential mechanisms of SGLT2i in anti-aging, offering valuable insights for anti-aging strategies and the prevention of aging-related diseases.
