Associations of the Geriatric Nutritional Risk Index(GNRI)and all-cause mortality risk in community-dwelling older adults
10.3760/cma.j.issn.0254-9026.2024.08.018
- VernacularTitle:老年营养风险指数与社区老年人群全因死亡风险的相关性研究
- Author:
Surui YANG
1
;
Chi ZHANG
;
Zhelin LI
;
Yiwen HAN
;
Ruiqi LI
;
Ping ZENG
Author Information
1. 北京医院 国家老年医学中心 北京协和医学院 中国医学科学院，北京 100730
- Keywords:
Geriatric Nutritional Risk Index;
All-cause mortality;
Older adults
- From:
Chinese Journal of Geriatrics
2024;43(8):1059-1064
- CountryChina
- Language:Chinese
-
Abstract:
Objective:The study aims to investigate the relationship between the Geriatric Nutritional Risk Index(GNRI)and the risk of all-cause mortality in older adults living in the community.Methods:Using data from the Chinese Longitudinal Healthy Longevity Survey.a community-based population cohort study utilized the Geriatric Nutritional Risk Index(GNRI), which was calculated based on height, weight, and serum albumin levels during baseline surveys conducted in 2012 and 2014.Participants were categorized into normal(GNRI>98), mild malnutrition(92 ≤ GNRI ≤ 98), and moderate/severe malnutrition(GNRI<92)groups.Follow-up of all participants continued until 2018, during which data on death outcomes and survival time were gathered.The study employed Kaplan-Meier curves and Cox proportional hazards regression models to assess the relationship between GNRI levels and the risk of all-cause mortality.Results:A total of 3, 016 older adults were analyzed, with 1, 296(42.97%)identified as having malnutrition.Over a follow-up period of 10, 594.5 person-years, there were 1, 280 deaths recorded.Adjusting for various factors such as sociodemographic characteristics, functional abilities, cognitive function, and chronic diseases, the mild malnutrition group showed a hazard ratio( CI)of 1.35(95% CI: 1.18-1.56)compared to the normal group, while the moderate/severe malnutrition group had a HR of 1.85(95% CI: 1.61-2.12)for all-cause mortality risk.The GNRI's area under the ROC curve for predicting death was 0.70(95% CI: 0.61-0.77), with a sensitivity of 71.3% and specificity of 65.4%.Subgroup analysis revealed a more significant association between malnutrition and mortality risk in men compared to women( P-interaction=0.037). Conclusions:The findings suggest a notable link between malnutrition levels and the risk of all-cause mortality, indicating that GNRI could be a valuable tool for predicting survival outcomes in this population.
