Advance in lipid metabolism and aging
10.3760/cma.j.issn.0254-9026.2024.08.006
- VernacularTitle:脂质代谢与衰老研究进展
- Author:
Xiahong LIN
1
Author Information
1. 中山大学附属第七医院老年医学科,深圳 518107
- Keywords:
Lipid metabolism;
Aging;
Cell senescence;
Senotherapeutics
- From:
Chinese Journal of Geriatrics
2024;43(8):988-993
- CountryChina
- Language:Chinese
-
Abstract:
The process of lipid metabolism, from lipid uptake to oxidation, as well as the enzymes and transporters involved in lipid metabolism, and different lipids, all participate into the regulation of aging.On the contrary, aging and longevity signals regulate lipid metabolism.Lipid metabolism reprogramming is involved in the formation and maintenance of senescent cells, and lipid components are potential targets for identifying senescent cells.Intervention in lipid metabolism can serve as a potential strategy for senolytics and senmorphics.