Clinical and imaging features of isolated infarction of the splenium of the corpus callosum and reversible splenial lesion syndrome
10.3760/cma.j.issn.0254-9026.2024.07.013
- VernacularTitle:孤立性胼胝体压部梗死与可逆性胼胝体压部病变综合征的临床及影像学特点分析
- Author:
Rui ZHU
1
;
Lei WANG
;
Miao WU
;
Miaomiao WANG
;
Jie ZHAO
;
Zhiyong ZHANG
Author Information
1. 北京老年医院神经内科，北京 100095
- Keywords:
Corpus callosum;
Isolated infarction of the splenium of the corpus callosum;
Reversible splenial lesion syndrome;
Magnetic resonance imaging
- From:
Chinese Journal of Geriatrics
2024;43(7):841-845
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the clinical characteristics and magnetic resonance imaging(MRI)features of isolated infarction of the splenium of the corpus callosum and reversible splenial lesion syndrome(RESLES).Methods:Clinical and imaging findings of 12 patients with a clinical diagnosis of isolated infarction of splenium of the corpus callosum and 13 patients with RESLES from Deportment of Neurology in Beijing Geriatric Hospital between December 2018 and November 2022 and follow-up results were retrospectively analyzed.Results:The patients with isolated infarction of SCC were older than the patients with RESLES(age of patients with isolated infarction of SCC: 67.6±9.2, age of patients with RESLES: 23.2±17.8).All patients with infarction had one to three risk factors for cerebrovascular diseases.Both two groups showed hyperintense lesions on T2WI, fluid-attenuated inversion recovery(FLAIR)and diffusion-weighted imaging(DWI), and hyperintense lesions on T1WI and a low apparent diffusion coefficient(ADC).Most SCC infarctions occurred unilaterally(one case with bilateral lesions and 12 cases with unilateral lesions), with irregular dot-like or patchy lesions.Nine patients in the infarction group completed the follow-up, during which the lesions did not disappear on the T1WI, T2WI, FLAIR and ADC sequence.One patient in this group had a recurrent stroke.In the RESLES group, all lesions were located on the midline of SCC, with round, oval or boomerang-shaped lesions.All patients in the RESLES group completed the follow-up, during which lesions either shrank or disappeared.Conclusions:Infarction and RESLES can both result in SCC lesions.The existence of risk factors and imaging features about the locations of lesions, the morphology, and lesion changes during follow-up are helpful in the differential diagnosis.
