Clinical characteristics and risk factors of patients with chronic heart failure and ischemic stroke
10.3969/j.issn.1009-0126.2024.09.010
- VernacularTitle:慢性心力衰竭合并缺血性脑卒中患者的临床特点及危险因素研究
- Author:
Qingyang ZHANG
1
;
Ye ZHU
;
Xiang GU
Author Information
1. 225001 扬州,江苏省苏北人民医院心血管内科
- Keywords:
heart failure;
stroke;
atrial fibrillation;
atrial flutter;
risk factors;
logistic models
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2024;26(9):1026-1030
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical features and related risk factors of chronic heart failure(CHF)patients with ischemic stroke.Methods A total of 153 elderly CHF patients with-out atrial fibrillation(AF)/atrial flutter(AFL)admitted in our hospital from January 2021 to January 2023 were enrolled,and according to diagnosis,they were divided into CHF group(84 cases)and ischemic stroke group(69 cases,CHF+ischemic stroke).General information,medical history and auxiliary examination indicators were collected.All of them were followed up for 6 months.SPSS statistical software was used to analyze the data of the 2 groups of patients,and the risk factors related to ischemic stroke were identified.Results Significant differences were observed in terms of age,hypertension,diabetes,partial thromboplastin time,left atrial diameter,left ventricular ejection fraction,right ventricular diameter,left ventri-cular end-systolic diameter,left ventricular end-diastolic diameter,CHF classification,thrombosis risk(CHA2DS2-VASc)score,HAS-BLED score,and usage of antiplatelet agents between the two groups(P＜0.05,P＜0.01).Multivariate logistic regression analysis showed that CHA2DS2-VASc score(OR=2.471,95％CI:1.356-4.502,P=0.003)and HAS-BLED score(OR=6.626,95％CI:2.049-21.432,P=0.002)were independent risk factors for ischemic stroke.ROC curve analysis indicated that the AUC value of CHA2DS2-VASc score and HAS-BLED score in predicting ischemic stroke in elderly CHF patients without AF/AFL was 0.936(95％CI:0.898-0.975,P＜0.01)and 0.922(95％CI:0.880-0.964,P＜0.01),respectively.Conclusion High CHA2DS2-VASc score and high HAS-BLED score are independent risk factors for ischemic stroke in elderly CHF patients with-out AF/AFL.
