Predictive value of blood pressure variability for long-term prognosis in elderly hypertension patients with coronary heart disease
10.3969/j.issn.1009-0126.2024.09.008
- VernacularTitle:血压变异性对老年冠心病合并高血压患者远期预后的预测价值
- Author:
Haiming LIU
1
;
Na ZHANG
;
Junshi ZHANG
Author Information
1. 830054 乌鲁木齐,新疆医科大学第一附属医院高血压科
- Keywords:
coronary disease;
hypertension;
prognosis;
forecasting;
blood pressure variability
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2024;26(9):1016-1019
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the predictive value of blood pressure variability for long-term prognosis in elderly hypertension patients with coronary heart disease(CHD).Methods A total of 272 elderly patients with CHD and hypertension admitted to our hospital from January 2015 to January 2018 were enrolled retrospectively,and all of them were followed up for 5 years.Accord-ing to that they had adverse cardiovascular events or not,they were divided into adverse cardio-vascular events group(n=102)and control group(n=170).The differences in clinical features were compared between the two groups.ROC curve was plotted to analyze the value of blood pressure variability at first admission in predicting adverse cardiovascular events in elderly hyper-tension patients with CHD.Multivariate logistic regression analysis was applied to identify the risk factors for adverse cardiovascular events in these patients.Results Compared with the con-trol group,the incidence of diabetes,the proportion of coronary artery stenosis＞75％,and 24-hour SBP variability were significantly higher in the adverse cardiovascular events group(P＜0.05,P＜0.01).The area under curve value of 24-hour SBP variability in predicting adverse cardio-vascular events in elderly patients with CHD and hypertension was 0.777(95％CI:0.720-0.835,P=0.000).24-hour SBP variability ≥11.71 mm Hg(1 mm Hg=0.133 kPa,OR=5.017,95％CI:2.911-8.647,P=0.000),diabetes(OR=2.479,95％CI:1.231-4.993,P=0.011),and coronary artery stenosis＞75％(OR=2.303,95％CI:1.022-5.190,P=0.044)were independent risk factors for adverse cardiovascular events in elderly patients with CHD and hypertension.Conclusion 24-hour SBP variability can be used to predict the occurrence of adverse cardiovascu-lar events in elderly hypertension patients with CHD.
