Risk factors for cerebral white matter hyperintensity without stroke syndrome
10.3969/j.issn.1009-0126.2024.08.017
- VernacularTitle:无脑卒中症候群脑白质高信号的危险因素分析
- Author:
Ting ZHANG
1
;
Xuanqin WANG
;
Li WANG
;
Junxia FENG
;
Junliang PU
Author Information
1. 743000 定西市人民医院神经内二科
- Keywords:
cerebral small vessel diseases;
magnetic resonance imaging;
logistics models;
risk fac-tors;
white matter hyperintensities
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2024;26(8):935-938
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the imaging features and risk factors of white matter hyperin-tensities(WMH)in elderly patients without stroke symptoms in Dingxi area.Methods A total of 253 elderly WMH patients without stroke syndrome admitted to our department from January 2020 to June 2022 were recruited,and according to Fazekas classification,they were divided into a control group(92 cases)and a study group(161 cases).The general clinical data were compared between the two groups.Multivariate logistic regression analysis was used to analyze the risk fac-tors of WMH,and Spearman correlation analysis was employed to analyze the correlation between WMH severity and hypertension.Results Older age,larger proportions of male and internal carotid plaques,and higher Hcy and TG levels were observed in the study group than the control group(P＜0.05,P＜0.01).Multivariate logistic regression analysis showed that age,TG,and Hcy were risk factors for WMH in elderly patients without stroke syndrome(OR=0.564,95％CI:0.338-0.942,P=0.029;OR=1.248,95％CI:1.153-1.351,P=0.000;OR=0.046,95％CI:0.016-0.132,P=0.000).The classification of hypertension had no correlation with the severity of WMH in elderly patients without stroke syndrome.Conclusion TG,Hcy and age are independ-ent risk factors for WMH in elderly patients without stroke symptoms.
