Predictive value of hs-cTnⅠ for short-term prognosis in patients with suspected acute coronary syndrome
10.3969/j.issn.1009-0126.2024.07.006
- VernacularTitle:高敏肌钙蛋白Ⅰ对疑诊急性冠状动脉综合征患者短期预后的预测价值
- Author:
Zebin GONG
1
;
Yan LIANG
;
Yahui LIN
;
Dongfang GAO
;
Qing YANG
;
Guangxun FENG
;
Tao ZHANG
;
Jun ZHU
;
Zhou ZHOU
Author Information
1. 100037 中国医学科学院北京协和医学院国家心血管病中心阜外医院心内科急重症中心
- Keywords:
acute coronary syndrome;
cardiac troponin I;
prognosis;
forecasting;
logistic models;
prospective studies
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2024;26(7):751-754
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the prognostic value of hs-cTnⅠ in patients with suspected acute coronary syndrome(ACS)in emergency department.Methods A large-scale,prospective observa-tional study was conducted on totally 966 patients with suspected ACS admitted in Fuwai Hospi-tal from January 2017 to October 2020.Their baseline serum/plasma hs-cTnⅠ level was detected at admission,conventional treatment was performed,and relevant data were collected.Logistic regression analysis was used to predict the risk of primary and secondary endpoint events within 30 d by hs-TnⅠ concentration,and subgroup analysis was performed.Results Among the 966 patients,the time from chest pain to visit was 5.0(2.5,13.0)h,and 284 patients had primary end-point events within 30 d,including 283 cases of myocardial infarction(99.6％)at the first visit,1 case of recurrent myocardial infarction(0.4％),5 cases of cardiovascular death(1.8％),and 1 case of unplanned revascularization(0.4％).When hs-cTnⅠ was at the minimum detection limit of 2 ng/L,the incidence of adverse events was 5.8％,when the limit of 70 ng/L,the incidence was 49.2％,and when of 316 ng/L,the incidence reached 100％.The model could correctly classify 92.3％of the patients.Conclusion The hs-cTn sequence has a good predictive effect for the risk of short-term cardiovascular adverse events in Chinese population.
