Comparative study of left bundle branch pacing in cardiac synchronization treatment system
10.3969/j.issn.1009-0126.2024.06.009
- VernacularTitle:左束支区域起搏应用于心脏同步化治疗系统的对比研究
- Author:
Hao LIANG
1
;
Xiang GU
;
Ye ZHU
Author Information
1. 225001 扬州大学附属苏北人民医院
- Keywords:
heart failure;
cardiac resynchronization therapy;
left bundle branch pacing
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2024;26(6):637-641
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical value of left bundle branch pacing(LBBP)in HF pa-tients requiring cardiac resynchronization therapy(CRT).Methods A total of 128 HF patients who met the indicatons for CRT Class Ⅰ and Ⅱ and admitted in Department of Cardiology of Northern Jiangsu People's Hospital from January 2018 to January 2023 were consecutively recrui-ted,and 32 patients of them having left bundle branch electrode implantation due to failure of cor-onary sinus electrode implantation were assigned into the LBBP group,and the rest 96 patients getting conventional biventricular pacing(BVP)into the BVP group.The pacing parameters and other indicators were observed in the two groups at the time of implantation.Follow-up visits were made to the Special Clinic of"Arrhythmia and Cardiac Pacemaker"in Northern Jiangsu People's Hospital at 1,3,6,and 12 months after surgery,and then,the visits were conducted every 3 to 4 months thereafter.Clinical evaluation,12-lead electrocardiography,echocardiography,detections for programmable controller and pacemaker function and other tests were completed at each follow-up.Readmission or death events due to HF were recorded.Results Compared with the preoperative results,both groups obtained shorter QRS duration,better NYHA class,smaller LVEDD and increased LVEF at the last follow-up(P<0.05).At the time point,shorter QRS du-ration,better NYHA class and higher LVEF were observed in the LBBP group than the BVP group(P<0.05).There were no significant differences in pacing parameters between the two groups at the time of implantation and the last follow-up(P>0.05).No statistical difference was found in readmission rate between the LBBP group and the BVP group(18.75%vs 16.67%,P>0.05).Conclusion LBBP is safe and effective,and can improve the cardiac function of HF pa-tients.LBBP may provide a new option for patients who have failed traditional CRT.