Establishment of a risk assessment model for long-term MACE based on global wall motion index
10.3969/j.issn.1009-0126.2024.06.006
- VernacularTitle:基于非梗死区心肌全壁运动指数建立主要不良心血管事件发生风险评估模型
- Author:
Youpeng WANG
1
;
Yibin PAN
Author Information
1. 321000 金华市中心医院心血管内科二区
- Keywords:
myocardial infarction;
percutaneous coronary intervention;
risk evaluation and mitiga-tion;
global wall motion index;
major adverse cardiovascular events
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2024;26(6):624-627
- CountryChina
- Language:Chinese
-
Abstract:
Objective To construct a risk assessment model for long-term MACE after PCI in acute myocardial infarction(AMI)patients based on global wall motion index(GWMI).Methods A to-tal of 350 AMI patients undergoing PCI in our hospital from May 2019 to May 2021 were en-rolled,and according to whether MACE occurred during follow-up period,they were divided into MACE group(82 cases)and non-MACE group(268 cases).Logistic regression analysis was used to identify the long-term risk factors,and a regression model of risk factors was constructed.Re-ceiver operating characteristic(ROC)curve analysis was applied to evaluate and compare the pre-dictive efficacy of our risk assessment model and Global Registry of Acute Coronary Events(GRACE)score for long-term MACE.Results The MACE group had significantly higher GRACE score,GWMI and B-type natriuretic peptide(BNP)level,and lower lymphocyte count,hemoglobin level and revascularization ratio than the non-MACE group(P＜0.05,P＜0.01).ROC curve analysis showed that the cutoff value of GWMI for predicting MACE was 1.04,and the AUC value was 0.747(95％CI:0.678-0.815).Multivariate logistic regression analysis indicated that BNP and GWMI were risk factors for MACE,while lymphocyte count,hemoglobin,and re-vascularization were protective factors for MACE(P＜0.05,P＜0.01).The regression equation for risk assessment model revealed that the AUC value in predicting MACE was 0.903(95％CI:0.862-0.952)for our risk assessment model and 0.757(95％CI:0.692-0.822)for GRACE score.Conclusion GWMI is an influencing factor for long-term MACE after PCI in AMI patients.A risk assessment model based on GWMI can effectively predict the risk of long-term MACE.
