Progress on the application of hepatitis B core antibody in special populations
10.3760/cma.j.issn.1674-2397.2024.03.009
- VernacularTitle:乙型肝炎核心抗体在特殊人群中的应用进展
- Author:
Zehua HONG
1
;
Yuanwang QIU
Author Information
1. 南京医科大学无锡医学中心，无锡 214023
- Keywords:
Hepatitis B;
Hepatitis C;
Hepatitis B core antibody;
Human immunodeficiency virus;
HBV reactivation
- From:
Chinese Journal of Clinical Infectious Diseases
2024;17(3):235-240
- CountryChina
- Language:Chinese
-
Abstract:
Hepatitis B virus core antibody（anti-HBc）is widely used in the disease staging，prediction of liver inflammation and fibrosis，antiviral efficacy and virus reactivation after drug withdrawal in patients with chronic hepatitis B（CHB）. Recent studies have found that the positive anti-HBc status may interact with disease progression and prognosis in patients with other viral infections（such as HCV，HDV and HIV），malignant tumors，autoimmune liver diseases，metabolic-associated fatty liver disease，and rheumatic diseases. This article reviews the research progress on the application of anti-HBc detection in these special patients，to provide reference for their disease assessment and clinical treatment.
