Risk factors of catheter-related thrombosis in femoral vein indwelling catheter for patients undergoing artificial liver therapy
10.3760/cma.j.issn.1674-2397.2024.03.004
- VernacularTitle:人工肝股静脉置管导管相关性血栓的影响因素分析
- Author:
Huafen ZHANG
1
;
Hui CHEN
;
Xin ZHANG
;
Liuyi WEI
;
Qinxian CHEN
;
Zhuoyao ZHANG
;
Xiaoyan WANG
;
Lihua HUANG
Author Information
1. 浙江大学医学院附属第一医院感染病科，杭州310003
- Keywords:
Artificial liver support therapy;
Femoral vein indwelling catheter;
Catheter-related thrombosis;
Risk factors
- From:
Chinese Journal of Clinical Infectious Diseases
2024;17(3):213-217
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the risk factors of catheter-related thrombosis（CRT）in femoral vein indwelling catheter for patients undergoing artificial liver therapy.Methods:The clinical data 1 060 patients who received non biological artificial liver therapy with femoral vein catheterization at the Artificial Liver Center of the First Affiliated Hospital，Zhejiang University School of Medicine from February 26，2019 to March 30，2022 were retrospectively analyzed. During the treatment，CRT occurred in femoral vein indwelling catheter in 574 cases（54.2%，CRT group）and did not occurred in remaining 486 cases（non-CRT group）. The influencing factors of CRT were analyzed with multiple Logistic regression.Results:Univariate analysis showed that gender，D-dimer before and after catheterization，international normalized ratio（INR），total bilirubin，catheterization location，and catheter retention time were significantly associated with the occurrence of CRT（all P<0.05）. Multiple Logistic regression analysis showed that male gender（ OR=1.627，95% CI 1.233-2.148， P<0.001），right femoral vein catheterization（ OR=2.101，95% CI 1.130-3.908， P=0.019），catheter retention time（ OR=1.039，95% CI 1.003-1.077， P=0.035），D-dimer >500 μg/L FEU after catheterization（ OR=1.697，95% CI 1.191-2.416， P=0.003）and INR≥1.5（ OR=1.343，95% CI 1.001-1.801， P=0.049）were independent risk factors for CRT in femoral vein indwelling catheter for artificial liver therapy. Conclusion:The incidence of CRT is high in patients undergoing artificial liver therapy with femoral vein catheterization. In clinical practice，medical staff should early identify high-risk populations for CRT and take timely preventive measures.
