The Characteristics of Capgras Syndrome in Patients Diagnosed as Probable Alzheimer Disease.
- Author:
Il Mi JANG
1
;
Hakjae ROH
;
Moo Young AHN
;
Young Soon YANG
;
Hae Ri NA
;
Sang Yun KIM
Author Information
1. Department of Neurology, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, Korea. imjang@schmc.ac.kr
- Publication Type:Original Article
- Keywords:
Capgras syndrome;
Dementia;
Alzheimer disease
- MeSH:
Alzheimer Disease;
Atrophy;
Brain;
Capgras Syndrome;
Dementia;
Follow-Up Studies;
Humans;
Magnetic Resonance Imaging;
Medical Records;
Neuroimaging;
Neuropsychological Tests;
Spouses
- From:Soonchunhyang Medical Science
2011;17(2):72-74
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: We assessed the characteristics of Capgras syndrome in patients diagnosed as probable Alzheimer disease, and compared the clinical and imaging findings with other previous reports. METHODS: We obtained medical records of patients with Capgras syndrome diagnosed as probable Alzheimer disease in three hospitals from March 2009 to March 2010. The basic characteristics, neuropsychologic tests, brain imaging data were investigated. RESULTS: The mean age of the patients was 74.7 years old and all of the patients experienced this syndrome in relation to a spouse. Brain magnetic resonance imaging showed mild-to-moderate global atrophy, variable hippocampal atrophy in this study. The Mini-Mental State Examination mean scores were 18.78 and clinical dementia rating scores were from 1 to 2. All of the patients took medicine of acetycholine esterase inhibitors and two patients recovered with antipsychotic medication. Five patients had showed continuous Capgras syndrome, at the last follow-up day, for a year. CONCLUSION: Capgras syndrome patients in this study who were diagnosed as probable Alzheimer disease showed similar results to the individuals from other reports. More study is needed to estimate the numbers and characteristics of patients with this syndrome.
