Risk factors for surgical site infection in liver transplant recipients: A meta-analysis
10.3760/cma.j.issn.1674-2397.2024.02.010
- VernacularTitle:肝移植受者手术部位感染危险因素荟萃分析
- Author:
Jianfen ZHOU
1
;
Mingyan SHEN
;
Tian HE
;
Linqiu HAN
Author Information
1. 浙江树人学院树兰国际医学院附属树兰杭州医院肝移植科，杭州 310022
- Keywords:
Liver transplantation;
Surgical site infection;
Risk factors;
Meta-analysis
- From:
Chinese Journal of Clinical Infectious Diseases
2024;17(2):150-155
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the risk factors for surgical site infections（SSI）in liver transplant recipients.Methods:Relevant studies on the risk factors for SSI in liver transplant recipients were searched in PubMed，Web of Science，EMbase，The Cochrane Library，CNKI，Wanfang，Vep，and the Chinese Biomedical Literature Database from inception to July 10，2023. The literature quality was assessed，and meta-analysis was performed using RevMan 5.4 and Stata 16 software.Results:A total of 10 studies involving 3 113 adult liver transplant recipients were included，and 723 cases of SSI were reported. Meta-analysis revealed that Roux-en-Y biliary reconstruction（ OR=2.60，95% CI 1.45-4.65），bile leakage（ OR=17.22，95% CI 8.48-34.96），repeat surgery（ OR=7.22，95% CI 4.25-12.26），re-transplantation（ OR=13.88，95% CI 7.71-24.97），prolonged surgical duration（ MD=0.52，95% CI 0.19-0.84），dialysis（ OR=3.44，95% CI 2.41-4.91），and extended hospital stay（ MD=11.42，95% CI 5.73-17.12）were independent risk factors for SSI in liver transplant recipients. Conclusion:The identified risk factors for SSI in liver transplant recipients include Roux-en-Y biliary reconstruction，bile leakage，repeat surgery，re-transplantation，prolonged surgical duration，dialysis，and extended hospital stay. Clinicians should enhance the assessment of these factors and take effective intervention to improve clinical outcomes for liver transplant recipients.
