Assessment of the prevalence and epidemiological characteristics of metabolic-associated fatty liver disease based on liver transient elastography
10.3760/cma.j.cn115624-20240911-00734
- VernacularTitle:基于肝脏瞬时弹性成像技术评估代谢相关性脂肪性肝病的患病状况及流行特征
- Author:
Rui YUAN
1
;
Jing GUI
;
Yan WANG
;
Yongxi ZHANG
;
Hengning KE
;
Yong XIONG
;
Rongrong YANG
Author Information
1. 武汉大学中南医院感染科，武汉大学艾滋病中心，武汉 430071
- Keywords:
Elasticity imaging techniques;
Fatty liver;
Body mass index;
Obesity;
Sex factors
- From:
Chinese Journal of Health Management
2024;18(12):894-898
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To better evaluate the prevalence and epidemiological characteristics of metabolic-associated fatty liver disease (MAFLD) based on liver transient elastography.Methods:It was a cross-sectional study. A total of 6 961 patients without hepatitis, who underwent liver transient elastography examination at the Department of Hepatology, Zhongnan Hospital of Wuhan University from November, 2021 to April, 2022 were included. The patients were categorized into normal and mild, moderate, severe MAFLD groups according to FibroTouch controlled attenuation parameters (CAP). The CAP values among different body mass index (BMI) groups were compared using analysis of variance. The distribution characteristics and the incidence of MAFLD in different age, gender, body mass index(BMI), blood glucose and lipids groups using the chi-square test.Results:The total detection rate of MAFLD and severe MAFLD in the population with a BMI≥28.0 kg/m 2 was 99.6% and 71.8%, respectively. The detection rate of MAFLD in people with normal BMI was 28.4%. The detection rate of MAFLD in women of childbearing age or in the perimenopausal period were both significantly lower than that in men of the same age (40.3% vs 54.9%, χ 2=20.78, P<0.001; 43.1% vs 58.4%, χ 2=27.43, P<0.001), but there was no statistically significant difference in MAFLD detection rate between postmenopausal women and men of the same age. The detection rates of MAFLD in the group with abnormal blood glucose and lipids were both significantly higher than those in the group with normal blood glucose and lipids [69.7%(196/281) vs 35.2%(2 354/6 680), χ 2=138.36, P<0.001; 54.3%(1 696/3 124) vs 37.1%(1 420/3 837), χ 2=207.99, P<0.001]. Conclusion:Non-hepatitis patients had a higher prevalence of MAFLD. The BMI, gender, age, blood glucose, and lipids levels are all strongly associated with MAFLD.
