Incidence and influencing factors of refeeding syndrome in critically ill patients:a Meta-analysis
10.3761/j.issn.0254-1769.2024.21.012
- VernacularTitle:重症患者再喂养综合征发生率及影响因素的Meta分析
- Author:
Xiaocui ZOU
1
;
Xiaorong MAO
;
Lixue WANG
;
Xiaojuan YANG
;
Qing WEN
Author Information
1. 610072 成都市 四川省医学科学院·四川省人民医院(电子科技大学附属医院)肝胆胰外科
- Keywords:
Refeeding Syndrome;
Incidence;
Influencing Factor;
Meta-Analysis;
Critical Care Nursing
- From:
Chinese Journal of Nursing
2024;59(21):2640-2648
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically review the incidence and influencing factors of refeeding syndrome(RFS)in critically ill patients,and provide references for early identification of RFS and formulation of preventive measures.Methods Computerized searches were conducted for studies on RFS in critically ill patients in the databases of China National Knowledge Infrastructure(CNKI),Wanfang,VIP,CBM,PubMed,Embase,Web of Science,CINAHL,Cochrane Library from inception to May 29th,2024.Data analysis was performed using Stata 16.0 software.Results A total of 29 articles with 5 720 participants were included.The Meta-analysis showed that the incidence of RFS in critically ill patients was 33.68％.The subgroup analysis showed that the incidence of RFS in critically ill patients was higher in studies conducted in 2020 or later(38.22％),in the Americas(36.39％),and with only electrolyte changes as the diagnostic basis(37.51％).Risk factors for RFS in critically ill patients included higher acute physiological and chronic health evaluation Ⅱ scores(OR=1.41),higher sequential organ failure assessment scores(OR=1.29),initiation of feeding within 48 h of ICU admission(OR=3.36),age ≥60 years(OR＝2.82),diabetes mellitus(OR=3.53),pre-albumin concentration＜150 g/L(OR=5.53),albumin concentration＜30 g/L(OR=3.26),caloric intake＞25％standard calories(OR=2.86),enteral solution temperature of 36～38 ℃(OR=2.32),feeding rate＞50 ml/h(OR=3.76),fasting time ≥2 d before feeding(OR=2.46),history of alcoholism(OR=2.64).Conclusion The incidence of RFS in critically ill patients is high and there are many influencing factors.Nurses should improve their awareness and attention to RFS,accurately identify high-risk groups and risk factors,and adopt a multidisciplinary collaborative model to develop whole-course,detailed and personalized intervention measures to prevent RFS.
