Construction and application of a non-drug intervention program for acute chemotherapy-related nausea and vomiting in children with cancer
10.3761/j.issn.0254-1769.2024.18.001
- VernacularTitle:肿瘤化疗患儿急性恶心呕吐非药物干预方案的构建及应用研究
- Author:
Luyan YU
1
;
Ying ZHOU
;
Jiajie FAN
;
Qian WU
;
Xiaoyi CHU
;
Tujun SHENG
;
Xi ZHANG
;
Guannan BAI
;
Nan LIN
;
Jihua ZHU
Author Information
1. 310052 杭州市 浙江大学医学院附属儿童医院神经外科
- Keywords:
Neoplasms;
Chemotherapy;
Nausea;
Vomiting;
Delphi Technique;
Pediatric Nursing
- From:
Chinese Journal of Nursing
2024;59(18):2181-2188
- CountryChina
- Language:Chinese
-
Abstract:
Objective To construct a non-drug intervention program for acute chemotherapy-related nausea and vomiting in children with cancer and to evaluate its efficacy.Methods Through literature review and Delphi expert correspondence,a non-drug intervention program for acute chemotherapy-related nausea and vomiting in children with cancer was constructed.By the convenience sampling method,200 consecutive children who received chemotherapy in the neurosurgery department of a tertiary children's hospital in Zhejiang province from February 1 to October 31,2023 were included as the application subjects,with 100 cases in an experimental group and 100 cases in a control group.The experimental group applied the non-drug intervention program of acute chemotherapy-related nausea and vomiting in children with cancer,and the routine measures were applied in the control group.The incidence of nausea and vomiting,severity of vomiting,compliance rate of normal sleep duration and incidence of negative emotions were compared between the 2 groups.Results The recovery rate of the valid questionnaire in 2 rounds of expert letter inquiry was 100％,and the expert authority coefficient was 0.836.The Kendall harmony coefficients were 0.471 and 0.820(P＜0.001),and the final non-drug intervention program for pediatric acute chemotherapy-related nausea and vomiting included 5 primary,14 secondary and 18 tertiary items.The results showed that the incidence of nausea,vomiting and negative emotions in the experimental group were lower than that in the control group,with statistically significant differences(P＜0.05).The severity of vomiting was less than it in the control group,with statistically significant difference(P＜0.05).The standard rate of normal sleep time was higher than that of the control group,and the difference was statistically significant(all P＜0.05).Conclusion The non-drug intervention program of chemotherapy-related nausea and vomiting in children is scientific and feasible,and the implementation of the program can reduce the incidence of nausea,vomiting and negative emotions,reduce the severity of vomiting,and improve the standard rate of normal bedtime in children.
