Laboratory Evaluation of Thrombophilic Factor in Retinal Vein Occlusive Disease.
- Author:
Ung Soo KIM
1
;
Sun Wook KIM
;
Seung Young YU
;
Hyung Woo KWAK
Author Information
1. Department of Ophthalmology, Kyung Hee University Hospital, Korea. hwkwak@khmc.or.kr
- Publication Type:Original Article
- Keywords:
Factor V Leiden;
Homocysteine;
Retinal vein occlusion;
Thrombophilic factor;
Young
- MeSH:
Antibodies, Anticardiolipin;
Antithrombin III;
Factor V;
Fibrinogen;
Homocysteine;
Humans;
Hyperlipidemias;
Lipoprotein(a);
Lupus Coagulation Inhibitor;
Platelet Aggregation;
Protein C;
Protein S;
Retinal Vein Occlusion;
Retinal Vein*;
Retinaldehyde*;
Thrombocytosis
- From:Journal of the Korean Ophthalmological Society
2003;44(9):2004-2009
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the significance of thrombophilic factors in retinal vein occlusive diseases. METHODS: Thirty-two patients with retinal vein occlusion (19 patients at the age of 55 or less, 13 patients at the age of 56 or more) underwent laboratory evaluation for CBC, lipid profile, VDRL/TPHA, homocysteine, protein C activity, protein S activity, lipoprotein (a), platelet aggregation test, Factor V Leiden, lupus anticoagulant, anticardiolipin antibody, fibrinogen, and antithrombin III. RESULTS: The abnormal laboratory findings (high homocysteine, hyperlipidemia, thrombocytosis, lipoprotein (a), high ESR, and decreased protein S activity) were found more often in patients of 55 years or less than those of 56 or more. CONCLUSIONS: The thrombophilic factors were more common positive findings at or less than 55 years. Thrombophilic factor tests are recommended in young patients with retinal vein occlusion.
