Influencing factors of frailty in lung transplant patients:a Meta-analysis
10.3761/j.issn.0254-1769.2024.09.015
- VernacularTitle:肺移植患者衰弱影响因素的Meta分析
- Author:
Peipei GU
1
;
Fei ZENG
;
Meijuan LAN
;
Jiangshuyuan LIANG
;
Luyao GUO
;
Lingyun CAI
;
Yan ZHU
;
Ge GUO
Author Information
1. 310000 杭州市,浙江大学医学院附属第二医院护理部
- Keywords:
Lung Transplantation;
Frailty;
Root Cause Analysis;
Meta-Analysis;
Evidence-Based Nursing
- From:
Chinese Journal of Nursing
2024;59(9):1122-1129
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify the factors associated with frailty in lung transplant patients by a meta-analysis.Methods Computerized search was performed for studies on the influencing factors of frailty in lung transplant patients in the CNKI,WanFangData,VIP,CBM,PubMed,Web of Science,Embase,Elsevier ScienceDirect and CINAHL databases.The search was conducted from the time of database construction to November 2023.Literature screening,quality assessment,and data extraction were performed independently by 2 investigators,and Meta-analysis was performed using Stata 17.0 software.Results 10 cohort studies,including 1 999 patients,were finally included,and 13 influencing factors were extracted,including advanced age(OR=1.05),female(OR=2.50),BMI(OR=0.38),diagnosis of primary pulmonary disease(OR=2.90),6MWD(OR=0.34),and lung allocation score(OR=0.69),FVC(OR=0.60),pre-transplant frailty(OR=0.81),hypoproteinemia(OR=4.12),hemoglobin(OR=0.50),anemia(OR=4.37),length of ICU stay(OR=1.24),and total length of stay(OR=1.05).Short Physical Performance Battery is an assessment tool for frailty in lung transplant patients,with an incidence of frailty in 24％before transplantation and 50％in post-transplantation.Fried Frailty Phenotype is an assessment tool for frailty in lung transplant patients,with a pre-transplant frailty incidence of 30％.Conclusion There are many factors involved in the incidence of frailty in lung transplant patients,and nursing staff should dynamically evaluate the frailty of lung transplant patients,and give individualized and precise interventions in combination with a multidisciplinary model to improve or delay the progression of frailty.
