Risk factors analysis of hepatic failure after major hepatectomy
10.3877/cma.j.issn.2095-3232.2018.02.014
- VernacularTitle:大范围肝切除术后肝衰竭危险因素分析
- Author:
Baiqiang ZENG
1
;
Xiang WU
;
Yihong RAN
;
Xuan LUO
;
Hongwei ZHANG
Author Information
1. 中山大学孙逸仙纪念医院肝胆外科
- Keywords:
Liver neoplasms;
Hepatectomy;
Liver failure;
Risk factors
- From:
Chinese Journal of Hepatic Surgery（Electronic Edition）
2018;7(2):143-146
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the risk factors of hepatic failure after major hepatectomy. Methods Clinical data of 293 patients receiving major hepatectomy in Sun Yat-sen Memorial Hospital of Sun Yat-sen University between January 2008 and February 2017 were retrospectively analyzed. The informed consents of all patients were obtained and the local ethical committee approval was received. According to whether there was postoperative hepatic failure, the patients were divided into the hepatic failure group and non-hepatic failure group. There were 23 cases in the hepatic failure group, including 22 males and 1 female with the mean age of (53±12) years. There were 270 cases in non-hepatic failure group, including 224 males and 46 females with the age of (49±12) years. Single factor analysis and Logistic regression analysis were used to analyze the risk factors of postoperative hepatic failure. Results The incidence of hepatic failure after major hepatectomy was 7.8% (23/293). Multi-factor Logistic regression analysis showed that preoperative Plt, Child-Pugh classification of liver function, tumor diameter and vascular tumor thrombus were the independent influence factors of postoperative hepatic failure (OR=0.983, 0.020, 0.726, 0.225;P<0.05). Conclusion Preoperative Plt, Child-Pugh classification of liver function, tumor diameter and vascular tumor thrombus are the independent influence factors of hepatic failure after major hepatectomy.
