Analysis on infection and drug resistance of Acinetobacter baumannii
10.3877/cma.j.issn.2095-3232.2016.05.012
- VernacularTitle:鲍曼不动杆菌感染和耐药性分析
- Author:
Jianrong LIU
1
;
Haijin LYU
;
Yuling AN
;
Xiaomeng YI
;
Xuxia WEI
;
Liang XIONG
;
Lijuan LI
;
Yingcai ZHANG
;
Yang YANG
;
Huimin YI
Author Information
1. 中山大学附属第三医院肝移植中心
- Keywords:
Acinetobacter baumannii;
Infection;
Multidrug resistance-associated proteins;
Liver transplantation
- From:
Chinese Journal of Hepatic Surgery（Electronic Edition）
2016;5(5):319-322
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the infection and drug resistance ofAcinetobacter baumannii in the Third Afifliated Hospital of Sun Yat-sen University.MethodsClinical data of 209 patients infected withAcinetobacter baumanniiin the Third Affiliated Hospital of Sun Yat-sen University between June 2012 and December 2014 were retrospectively analyzed. Among the patients, 160 were males and 49 were females with the average age of (55±18) years old. The informed consents of all patients were obtained and the local ethical committee approval was received. The specimen source, ward distribution and drug resistance of Acinetobacter baumannii were observed. The comparison of drug resistance was conducted using Chi-square test and Bonferroni test.ResultsTwo hundred and thirty-six strains ofAcinetobacter baumannii were isolated in the hospital, and most were isolated from Department of Liver Transplantation (50 strains, 21.2%), the next were Department of Rehabilitation (34 strains, 14.4%) and Surgical Intensive Care Unit (SICU) (21 strains, 8.9%). Sputum specimens were the main source ofAcinetobacter baumannii, respectively accouting for 84%, 76% and 71% in the three wards, whereAcinetobacter baumannii had high drug resistance to the common antibiotics used in clinical. The drug resistance rate to sulfamethoxazole ofAcinetobacter baumannii in Department of Liver Transplantation was 76%, signiifcantly higher than 33% of SICU (χ2=11.60,P<0.017).ConclusionsAcinetobacter baumannii is found most in Department of Liver Transplantation, which is followed by Department of Rehabilitation and SICU. Sputum specimen is the main source ofAcinetobacter baumannii.Acinetobacter baumannii detected in the three wards has a high drug resistance to common antibiotics.
