Diagnosis and treatment of primary hepatic lymphoma
10.3877/cma.j.issn.2095-3232.2016.03.011
- VernacularTitle:原发性肝淋巴瘤诊断与治疗
- Author:
Lihua XU
1
;
Ruiming LIU
;
Qunai HUANG
;
Ruilei LIU
Author Information
1. 510230广州医科大学附属第一医院血液科
- Keywords:
Liver neoplasms;
Lymphoma;
Diagnosis;
Chemotherapy,adjuvant
- From:
Chinese Journal of Hepatic Surgery（Electronic Edition）
2016;5(3):173-176
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo investigate the clinical diagnosis, treatment and prognosis of primary hepatic lymphoma (PHL).MethodsClinical data of 9 patients with PHL who admitted and treated in the Third Affiliated Hospital of Sun Yat-sen University between March 2008 and December 2015 were retrospectively analyzed. Among the patients, 6 were males and 3 were females with the age ranging from 46 to 61 years old and the median of 53 years old. The informed consents of all patients were obtained and the local ethical committee approval was received. The clinical manifestation, diagnosis procedure, therapeutic regimen and prognosis of the patients were analyzed.ResultsAmong the 9 patients, 4 cases saw the doctor for the ifnding of a hepatic space-occupying lesion, 3 cases for epigastric pain, and 2 cases for fever. Nine cases were complicated with chronic viral hepatitis B (HBV). Elevated preoperative serum lactate dehydrogenase was observed in 3 cases. Ultrasound examination indicated a hypoechoic echogenic mass in the liver, and plain CT scan indicated a low-density lesion in the liver. The diagnosis of all 9 patients was confirmed by the pathological examination. Two cases underwent simple resection, 2 underwent resection + chemotherapy and 5 underwent liver biopsy + chemotherapy. By the paper submission date, 6 patients survived and 4 of them survived more than 12 months.ConclusionsThe clinical manifestation and imaging ifndings of PHL are non-speciifc. Conifrmed diagnosis depends on the pathological examination, and surgical resection combined with chemotherapy is an effective treatment.
