Characteristics of symptom distress and its inlfuencing factors in patients with primary liver cancer after transcatheter arterial chemoembolization
10.3877/cma.j.issn.2095-3232.2014.02.008
- VernacularTitle:原发性肝癌经导管动脉化疗栓塞术后患者症状困扰特点及其影响因素
- Author:
Xuehua WANG
1
;
Wenyan CHENG
;
Huiling ZHANG
;
Shiju HUANG
Author Information
1. 中山大学附属第三医院肝胆外科
- Keywords:
Carcinoma,hepatocellular;
Radiology,interventional;
Signs and symptoms,digestive;
Symptom distress;
Social support
- From:
Chinese Journal of Hepatic Surgery（Electronic Edition）
2014;(2):96-99
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the characteristics of symptom distress and its inlfuencing factors in patients with primary liver cancer after transcatheter arterial chemoembolization (TACE). Methods A total of 108 patients with primary liver cancer receiving TACE in Department of Hepatobiliary Surgery, the Third Afifliated Hospital of Sun Yat-sen University from January 2012 to January 2013 were voluntarily enrolled in this study on the 3rd day after operation by convenience sampling method. There were 94 males and 14 females with age ranging from 26 to 72 years old and median age of 51 years old. The informed consents of all patients were obtained and the ethics committee approval was received. Cross-sectional study and questionnaire survey were used in the research. The questionnaire survey included questionnaire of general information, M.D. Anderson Symptom Inventory (MDASI), Social Support Measuring Questionnaire (SSS) and Medical Coping Modes Questionnaire (MCMQ). Multiple linear regression analysis was used to identify factors inlfuencing the symptom distress. Results The mean score of MDASI symptom subscale of patients during therapy was 3.0±1.6 with a mild degree of symptom distress. The score of MDASI life distress subscale of patients was 3.4±1.7, also with a mild degree of symptom distress. Work was most influenced by the symptoms, followed by emotion, joy of life, common activity, relation with others and walks. Fever, discomfort of stomach, abdominal distention, icteric skins and weight loss were common symptoms in sequence which distressed patients. The total score of social support was 42.2±6.7 which was at the middle level, and the sore of use of social support was 7.9±2.2. The score of 3 dimensions facing, avoiding, surrender were 2.5±0.5, 2.4±0.5, 2.0±0.6 respectively. Facing and avoiding were the common coping modes. Patients who had college educational degree or above, no job after being ill, low level of subjective support, surrender coping mode were more distressed by symptoms than the other patients (RR=0.320, 0.254, 0.569, 0.217;P<0.05). Conclusions Patients with primary liver cancer have mild symptom distress after TACE, and patients with college educational degree or above, no job after being ill, low level of subjective support, surrender coping mode are more distressed by symptoms than the other patients.
