Advances in the treatment of advanced unresectable intrahepatic cholangiocarcinoma
10.3760/cma.j.cn113884-20240430-00131
- VernacularTitle:晚期不可切除肝内胆管癌的治疗进展
- Author:
Qingze LI
1
;
Guofei DONG
;
Qisheng HAO
;
Xinyu LI
;
Mingkai GONG
;
Lichao CHA
;
Lantian TIAN
Author Information
1. 青岛大学附属医院肝胆胰外科,青岛 266000
- Keywords:
Bile duct neoplasms;
Targeted therapy;
Immunotherapy;
Chemotherapy;
Radiotherapy
- From:
Chinese Journal of Hepatobiliary Surgery
2024;30(9):714-720
- CountryChina
- Language:Chinese
-
Abstract:
Intrahepatic cholangiocarcinoma (ICC) is a highly malignant tumor with poor prognosis. In the process of clinical diagnosis and treatment, only a small number of patients can receive surgical treatment in time, and the rest often have local infiltration or distant metastasis at the time of presentation, which can only prolong the overall survival by adjuvant therapy. At present, the main adjuvant treatments in clinical practice include chemotherapy, targeted therapy and immunotherapy. This article reviews the progress of systemic therapy and some clinical trials in patients with advanced unresectable ICC, to provide a reference for the clinical diagnosis and treatment of ICC.