Research progress on the role of gut microbiota in liver regeneration
10.3760/cma.j.cn113884-20240311-00068
- VernacularTitle:肠道菌群在肝脏再生中的研究进展
- Author:
Linyan ZHOU
1
;
Yongnan LI
;
Jian LI
;
Zuoyi JIAO
Author Information
1. 兰州大学第二医院普通外科，兰州 730030
- Keywords:
Gastrointestinal microbiome;
Liver injury;
Liver regeneration
- From:
Chinese Journal of Hepatobiliary Surgery
2024;30(8):620-625
- CountryChina
- Language:Chinese
-
Abstract:
The liver's remarkable regenerative capacity is crucial to restore its function, which can be compromised in cases of severe or chronic liver injury. Thus, the search of new methods to promote liver regeneration is of great clinical importance. In recent years, the gut microbiota is an emerging field of research that attracts the scientific community. The gut microbiota not only affects the integrity of digestive system but also exerts a significant impact on liver function via the so-called " gut-liver axis". Increasing evidence suggests that an imbalance in gut microbiota is associated with the development of various liver diseases, and modulation of gut microbiota might be a potential cure for liver diseases. Research into the role of gut microbiota in liver regeneration not only help us understand the pathogenesis of liver diseases but also facilitate the development of new therapeutic strategies.
