Analysis of the efficacy of laparoscopic radical surgery for incidental gallbladder cancer following cholecystectomy
10.3760/cma.j.cn113884-20240409-00100
- VernacularTitle:胆囊切除术后意外胆囊癌患者再次行腹腔镜胆囊癌根治术的疗效分析
- Author:
Tianyu CHEN
1
;
Ziyu LIU
;
Mengqiu YIN
;
Xi CHEN
;
Ruibiao FU
;
Chongyu WANG
;
Jun LI
;
Jinhui ZHU
Author Information
1. 浙江大学附属第二医院肝胆胰外科，杭州 310000
- Keywords:
Gallbladder neoplasms;
Laparoscopic cholecystectomy;
Reoperation;
5-year survival rate
- From:
Chinese Journal of Hepatobiliary Surgery
2024;30(6):412-416
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the efficacy of laparoscopic radical surgery, compared to open surgery, for incidental gallbladder cancer following cholecystectomy.Methods:Clinical data of 106 patients with incidental gallbladder cancer treated at the Second Affiliated Hospital Zhejiang University School of Medicine from April 2010 to February 2018 were retrospectively analyzed, including 66 males and 40 females, aged (64.7±7.9) years old. According to surgical approach, patients were divided into the laparoscopic group ( n=45) and open group ( n=61). Perioperative data, including intraoperative blood loss, postoperative hospital stay, and postoperative complications, were compared between the groups. Follow-ups were conducted via outpatient visits or telephone reviews. Survival analysis was performed using the Kaplan-Meier method, and the survival rates were compared using the log-rank test. Results:All 45 patients in the laparoscopic group successfully underwent the surgery without conversion to open surgery. Compared to the open group, the laparoscopic group had a reduced intraoperative blood loss [(100±25) ml vs. (200±46) ml] and a shortened postoperative hospital stay [3(2, 5) d vs. 5(4, 7) d] (both P<0.05). The postoperative complication rates were 6.7% (3/45) in the laparoscopic group and 13.1% (8/61) in the open group ( χ2=4.16, P=0.041). The cumulative survival rate after radical surgery for incidental gallbladder cancer was better in the laparoscopic group ( χ2=4.58, P=0.032). Conclusion:Compared to open surgery, laparoscopic radical surgery for incidental gallbladder cancer showed benefits in intraoperative blood loss, postoperative hospital stay, complication rates, and cumulative survival.
