Research progress in radiation-induced small intestine injury
10.3760/cma.j.cn113030-20240618-00236
- VernacularTitle:放射性小肠损伤的研究进展
- Author:
Fuhao WANG
1
;
Ye ZHANG
;
Qifeng WANG
;
Pei YANG
;
Wencheng ZHANG
;
Jinbo YUE
Author Information
1. 山东省肿瘤防治研究院（山东省肿瘤医院）腹部放疗一病区，山东第一医科大学（山东省医学科学院），济南 250117
- Keywords:
Neoplasms;
Radiotherapy;
Radiation injury;
Intestinal side effects;
Research progress
- From:
Chinese Journal of Radiation Oncology
2024;33(11):1016-1023
- CountryChina
- Language:Chinese
-
Abstract:
Surgery, radiotherapy and chemotherapy are currently the principal modalities for oncological treatment. Approximately 70% of patients with malignant tumors require radiotherapy. However, the damage induced by radiation on normal human tissues remains an unavoidable issue in clinical practice. When radiotherapy is applied to abdominal and pelvic tumors such as liver cancer, colorectal cancer, cervical cancer, and prostate cancer, the anatomical proximity of these organs to the small intestine inevitably leads to some degree of intestinal damage. This type of injury, induced by radiotherapy, is referred as radiation-induced small intestine injury. Clinically, a high incidence of radiation-induced small intestine injury is observed among patients receiving pelvic and abdominal radiotherapy, which not only impacts the quality of life of cancer patients, but also limits the effectiveness of the treatment. This article reviews the research progress in radiation-induced small intestine injury.
