Research progress in radiation-induced dysphagia
10.3760/cma.j.cn113030-20240311-00094
- VernacularTitle:放射性吞咽困难的研究进展
- Author:
Shunxin WANG
1
;
Yiming LEI
;
Yi YANG
;
Lei CHEN
;
Pei YANG
;
Jinbo YUE
;
Ye ZHANG
;
Wencheng ZHANG
;
Qifeng WANG
;
Yanping MAO
Author Information
1. 中山大学肿瘤防治中心放疗科,广州 510060
- Keywords:
Head and neck neoplasms;
Radiotherapy;
Radiation injury;
Dysphagia;
Research progress
- From:
Chinese Journal of Radiation Oncology
2024;33(11):999-1006
- CountryChina
- Language:Chinese
-
Abstract:
Dysphagia is the main complication of chemoradiotherapy for head and neck cancer. Recently, the advancement of multidisciplinary treatment has achieved a higher tumor control rate, but also a higher incidence of late radiation-induced dysphagia in head and neck cancer. Radiation-induced dysphagia leads to prolonged unnatural feeding, nutritional deficiency, weight loss, and also has a major risk for silent aspiration and aspiration pneumonia, which significantly reduces the quality of life of patients. Besides, late radiation-induced dysphagia is the main reason for limiting the intensity of treatment. Therefore, it is of great significance to deeply understand the pathogenesis of radiation-induced dysphagia and actively explore effective prevention and treatment measures to improve the survival rate and quality of life in head and neck cancer. This paper summarizes the pathogenesis, occurrence, risk factors of radiation-induced dysphagia in head and neck cancer, as well as the progress in the measurement and reporting methods, prevention and treatment strategies.