Research progress in radiotherapy for brain metastases from driver gene-negative non-small cell lung cancer

VernacularTitle:驱动基因阴性非小细胞肺癌脑转移放射治疗的研究进展
Author: Huiling LIU ¹ ; Mi LAO ; Xiaoping CAI ; Yong YIN ; Ruozheng WANG
Author Information

1. 山东省滨州市人民医院肿瘤科，滨州　256600
Keywords: Carcinoma, non-small-cell lung; Driver gene-negative; Brain metastasis; Radiotherapy
From: Chinese Journal of Radiation Oncology 2024;33(8):766-771
CountryChina
Language:Chinese
Abstract: The incidence and mortality of lung cancer rank first among malignant tumors in the world worldwide. Non-small cell lung cancer (NSCLC) is the main pathological type, with a significant proportion being driver gene-negative NSCLC. When accompanied by brain metastasis, radiotherapy is the optimal local therapy, apart from surgery, and which is widely used applied in clinical practice. With the continuous development of technology and drugs, the survival of patients with brain metastases has been generally improvedprolonged. In the era of precision medicine, the concept and technology of radiotherapy are evolving towards precision and diversification. In this article, the evolution of radiotherapy techniques and its combined application with other treatment methods were reviewed, aiming to provide references for the selection of radiotherapy protocol for driver gene-negative NSCLC patients with brain metastases in clinical practice.